Day four of Wimbledon witnessed the first major shock as French Open champion Garbine Muguruza fell to an early exit with defeat to Jana Cepelova.
Last year’s runner-up Muguruza was a shadow of her usual self as the Slovak pulled off a major upset in convincing fashion with a 6-3 6-2 victory over the Spaniard to reach the third round.
It was also the end of the road for British number one Johanna Konta as Canadian Eugenie Bouchard edged out the 16th seed 6-3 1-6 6-1 to book a place in round three.
Heather Watson followed her compatriot Konta out of Wimbledon, as Germany’s Annika Beck came from a set down to edge past the British number two 3-6 6-0 12-10 in their first round match.
Five-time champion Venus Williams was made to work for her place in the third round with a 7-5 4-6 6-3 win over 20-year-old Greek qualifier Maria Sakkari, while fellow American Madison Keys also had to dig deep against Belgian Kirsten Flipkens to secure a 6-4 4-6 6-3 victory.
Australian Open champion Angelique Kerber encountered no problems in her routine 6-1 6-4 win over American Vavara Lepchenko, while fifth seed Simona Halep cruised past Italian Francesa Schiavone 6-1 6-1 to reach the third round.
Poland’s Agnieszka Radwanska overcame a second set scare against Ana Konjuh of Croatia to seal her place in the third round with a 6-2 4-6 9-7 victory, but 20th seed Sara Errani is out after Alize Cornet sent the Italian home with a 7-6 (7/4) 7-5 win for the French woman.
11th seed Timea Bacsinszky overcame Thai Luksika Kumkhum 6-4 6-2 in her rain-delayed first round match, but fellow Swiss woman Belinda Becic is out as the seventh seed had to retire due to injury while trailing 6-4 1-0 to American Julia Boserup.
Spain’s Carla Suarez Navarro overcame an early scare in her 3-6 6-2 6-1 win over Czech Denisa Allertova, while Aussie Sam Stousr is out after a 4-6 2-6 defeat to German Sabine Lisicki.
In men’s action, it was all to easy for second seed Andy Murray who cruised into the third round with a comfortable 6-3 6-2 6-1 win over Chinese Tapei’s Yen-Hsun Lu to keep hopes of winning a third grand slam alive.
Kei Nishikori came from a set down in his second round match against France’s Julien Benneteau 4-6 6-4 6-4 6-2, while Croatia’s Marin Cilic also had to dig deep to beat Ukraine’s Seriy Stakhovsky 6-2 6-7 (6/8) 6-4 6-4.
David Ferrer is out of the tournament after Frenchman Nicolas Mahut stunned the 13th seed in straight sets 6-1 6-4 6-3 to reach the third round, while there was also an early exit for Gilles Simon as Bulgarian Grigor Dmitrov ousted the 16th seed 6-3 7-6 (7/1) 4-6 6-4.
Highly rated Austrian Dominic Thiem also crashed out at the second round as Czech Jiri Vesley edged past the eighth seed 7-6 (7/4) 7-6 (7/5) 7-6 (7/3), as seventh seed Richard Gasquet battled from a set down to beat Spain’s Marcel Granollers 4-6 7-5 6-3 6-1.
There was better news for Canadian Milos Raonic who overcame Italian Andreas Seppi in straight sets 7-6 (7/5) 6-4 6-2, while Belgian David Goffin also sailed through with a 6-4 6-0 6-3 victory over France’s Edoard Roger-Vasselin.
American John Isner needed two tie-breaks to book his place in the second round with a hard-fought 7-6 (7/2) 7-6 (77/5) 6-3 win over Cypriot Marcus Baghdatis, while 19th seed Bernard Tomic saw off the challenge of Moldovan Radu Albot 7-6 (7/3) 6-3 6-7 (6/8) 6-3.
Great Britain’s Dan Evans set up a third round clash with third seed Roger Federer as the 26-year-old saw off Ukrainian Alexandr Dolgopolov 7-6 (8/6) 6-4 6-1 in straight sets.